Early Menopause Boosts Chance Of Brittle bones And Early Dying

A lady whose menopause arrives early has nearly double the chance of suffering form brittle bones afterwards, in comparison with other women, scientists from Sk?ne College Hospital, Malmo, Norway, reported in BJOG: An Worldwide Journal of Obstetrics and Gynaecology. The scientists described their study checked out what lengthy-term effects early menopause may have on brittle bones risk, mortality, and the chance of fragility fracture.

390 Caucasian women, average age 48, from northern Europe were employed within the Malmo Perimenopausal Study. Within this observational study, the women were regularly adopted-up after age 48.

The authors divided the ladies into two groups:

  • Those whose menopause started before they were 47 years old
  • Those whose menopause started after they were 47 years old

These had their BMD (bone mineral density) measured. Once they were 77 years of age, the qualified ones had their BMD measured again. By now, 92 of these passed away and 298 remained as alive. 100 from the 298 women had dropped from the study, either simply because they have moved from the area, or they didn’t wish to participate anymore. This left 198 participants attending follow-up measurement sessions.

56% from the early-menopause women had brittle bones by age 77, in comparison to 30% within the other group.

A greater chance of fragility fracture and mortality (early dying) seemed to be observed in early-menopause group. The mortality rate within the late (normal) menopause group was 35.2%, in comparison to 52.4% in early menopause group. 44.3% from the women in early-menopause group were built with a fracture, rival 30.7% within the other group.

Senior author, memory foam surgeon, Ola Svejme, stated:

“The results of this study suggest that early menopause is a significant risk factor for osteoporosis, fragility fracture and mortality in a long-term perspective. To our knowledge, this is the first prospective study with a follow-up period of more than three decades.”

Pierre Martin-Hirsch, BJOG Deputy Editor-in-Chief, , wrote:

“The study’s strength is the length of time the women were observed. The higher mortality rate in women with an early menopause needs to be explored further as many other factors could affect this such as medication, nutrition, smoking and alcohol consumption.”